When to Take BCAAs: Pre- or Post- Workout? Morning, Noon or Night?

When is the best time to take BCAA supplements: pre-, during, or post-workout? Is it safe to consume them before bed? What about in between meals? We have the science and the answers.

There are many reasons to take protein supplements, and not all of them have to do with working out. Vegetarians and vegans often take them to make sure they’re getting enough plant-based protein. Those recovering from surgery are often on doctor’s orders to consume more protein to help heal faster. Those working to lose weight also find that consuming more protein helps fuel their energy and their weight-loss efforts by curbing hunger and increasing muscle growth. All of the above is even more true for those who consume protein like whey, creatine, or BCAAs (branched-chain amino acids) to boost their workout or to build muscle: you need enough protein to function, you need even more protein for recovery, and you need to control your calorie consumption as you aim to bulk up. If you’re new to trying BCAAs, the first question you have after what they are and how do they work is likely to be: when to take BCAAs? We have the best practical advice here.

Muscles, Amino Acids, and BCAAs

Muscles are made out of protein, and protein is made out of amino acids. Specifically, the human body needs all nine essential amino acids (EAAs) to synthesize any new muscle protein. Of those nine essentials (as opposed to the nonessential amino acids that your body can make on its own, meaning it’s not essential to consume them in food), three are branched-chain amino acids, so called because of their molecular structure.

So what are the three BCAAs and why are they singled out for workout supplements? Let’s start with their names.

  • Leucine: This is the amino acid thought to make the biggest difference when it comes to building new muscle proteins.
  • Isoleucine: An isolated form of leucine (hence its name), isoleucine helps regulate blood sugar levels and energy production.
  • Valine: This BCAA is important not only for maintaining muscles but also for supporting immune function.

Together these three aminos make up about 40% of the EAAs in the body, and about 18% of the EAA content of muscle. They are broken down in the skeletal muscles directly instead of in the liver with the majority of the other EAAs, which leads researchers to theorize that they play a more direct part in energy production during exercise. Not only are BCAAs essential building blocks for protein synthesis and muscle growth, but they also positively impact your blood sugar levels and help ward off exercise fatigue.

All of the essential amino acids depreciate more rapidly during exercise due to a protein breakdown process known as catabolism (more on this later). If you are fit, active, and looking to build more muscle, you’ll want to increase protein-rich foods in your diet, which is why taking targeted amino acids like BCAAs is so popular among fitness aficionados.

Muscles, Amino Acids and BCAAs

The Scientifically Proven Benefits of BCAA Supplementation

Here’s a quick rundown on the science behind BCAAs, and why so many professional bodybuilders use them.

1. Increased Muscle Growth

Leucine particularly has been shown time and time again to stimulate new muscle protein synthesis. This 2017 study showed that those taking 5.6 grams of BCAAs post-workout enjoyed an increase in muscle protein synthesis 22% higher than the control group.

2. Decreased Exercise Fatigue and Muscle Soreness

Some fatigue will always be a part of a proper workout: if you’re not at all tired after a workout, you’re probably not doing it right! But exercise fatigue that sets in too soon or when your workout is hardly begun? You may be suffering from a low energy source, and that is where BCAAs can come in swinging.

Studies show that when your BCAA levels decrease, your tryptophan levels increase in the brain. Tryptophan is the amino acid that famously makes a turkey dinner so sleep-inducing. Tryptophan is converted to serotonin, and serotonin leads to feelings of fatigue and lethargy.

Because BCAAs are burned up in the muscles during a vigorous workout, making sure your body has more than enough to burn through helps delay exercise fatigue, providing time for a few more reps or a few more steps.

BCAAs can also help mitigate delayed onset muscle soreness (DOMS), so that you can go strong with more workouts per week because you aren’t still achingly sore from the last one. BCAAs have not only been shown to decrease muscle damage and protein breakdown during workouts, but they also lead to fewer reported instances of delayed onset muscle soreness when tested against a control group.

3. Prevention of Muscle Wasting

While muscle protein is forever in a cycle of build-up and breakdown, actual muscle wasting occurs when protein breaks down at a far faster pace than it can be rebuilt. It happens to those who are malnourished or fasting excessively, as well as to the sick and the elderly. But it can also happen to those who overexert themselves in workouts.

During times of muscle wasting, it’s important to resupply the body with the building blocks of protein that are the amino acids, which includes BCAAs. Studies reveal that one of the effects of BCAA supplementation is to inhibit muscle protein breakdown, not only in those seeking to gain muscle with resistance training or reach new heights with endurance exercise, but also in those with cancer and other wasting diseases.

Counterbalancing Catabolism

Muscle breakdown is known as “destructive metabolism” or catabolism, and while it’s a process that bodybuilders do their best to ward off, it’s also part of the natural cycle between catabolism and anabolism.

Muscle protein turnover is not unlike the regenerative properties of a forest fire. Balance is the key. Catabolism of protein molecules that are old or damaged is great; it clears the dead wood and repurposes those nutrients for healthy new growth. However, when your body doesn’t have enough amino acids to build with, unlike a forest it will start chopping down healthy molecules to meet the production demand of new lean muscle mass. This is why the timing of protein supplements like BCAAs is important.

That being said, it should be noted that an abundance of BCAAs without the rest of the nine essential amino acids will not effectively prevent unnecessary catabolism. Think of building new muscle like building furniture (perhaps with wood from the above-mentioned forest metaphor): the BCAAs are the different cuts of wood for the frame, but without cushions, fabric, springs, wood glue, nails, and screws, would you have a new couch, or just an overabundance of wood?

For this reason, we suggest taking BCAAs as part of a balanced formula of all the EAAs, because if the body lacks any one ingredient, it will burn down your hard-earned muscle tissue to take it.

Still don’t believe us? While studies on BCAA supplementation confirm that they boost muscle protein synthesis much better than a placebo, that boost is still 50% lower than the boost seen in studies with whey protein, which contains some measure of all nine essential amino acids. Taking anything less than all the EAAs is scientifically considered suboptimal, an important aspect to keep in mind when selecting the most robust and effective protein powder for your muscle-building workout.

Counterbalancing Catabolism

When to Take BCAAs

If you’ve decided BCAAs are what’s missing from your workout routine, the question still remains: when is the best time to take protein for optimal exercise performance, body fat loss, and muscle growth? The quick answers are:

  • Pre-workout: Always, for everything. To make sure you have the supplies on-hand for the vigors of your workout, take between 5 and 10 grams (depending on your body weight) of amino acids within half an hour before your workout. This helps boost your energy, endurance, and muscle recovery speed.
  • During workout: For resistance exercise and longer workouts, another dose of BCAAs can help see you through to the end and keep your muscles in A+ anabolic territory.
  • Post-workout: Across the board, yes again. While timing may vary, consuming more protein in the form of amino acids after any workout contributes to the rebuilding efforts of your muscles.
  • Before bed: This one is for bodybuilders in particular. Consuming complex proteins your body can digest while sleeping helps prevent catabolism while you rest.

The more fat burning and bodybuilding you do, the more nutrients you will need from both whole food sources and amino acid supplements. This could mean supplementing with meals or between meals multiple times a day depending on your body, your body goals, and your workout regimen. When it comes to sports nutrition, fitness professionals, athletes, or those undergoing rigorous training periods may need to consume anywhere between 15 and 20 grams of BCAAs along with other proteins each day, far more than those who are working out a handful of times or fewer per week to stay in shape throughout their daily lives.

When to take BCAAs for muscle building?

Boosting with BCAAs

The amino acids leucine, isoleucine, and valine are the core components of BCAA supplements, and while their effectiveness is proven in the areas of fitness and muscle building, it’s also known that BCAA powders or supplements alone underperform when compared to more comprehensive EAA supplements and proteins. Take your BCAAs, but take them alongside the rest of their essential team for optimal results.

Building Muscle After 50: Top 7 Tips to Go from Sedentary to Stacked

Discover how to build muscle and maintain strength after turning 50: types of workouts, frequency of workouts, and how to supplement effectively now that you’re half a century strong.

One of the biggest concerns that face us as we age is muscle loss. Age-related muscle loss begins in our 30s and ramps up after 50. In advanced years that muscle loss can ultimately contribute to frailty if it’s not combated with proactive muscle building along the way. While those who have kept up with physical activity throughout their 20s and 30s have a much better foundation to build on, it’s never too late to begin weight training or resistance training, gaining muscles that get stronger the more they’re used. Because of these reasons, building muscle after 50 is necessary to keep you healthy and active for the rest of your life.

Sarcopenia: The Silent Breakdown

Age-related muscle loss is known as sarcopenia, and it’s one of the reasons that some of our grandparents lose their independence. The muscle loss that begins in our 30s and doubles down in our 50s gets even more aggressive after 70, but it’s not necessarily a downward slope. Studies show that we can gain muscle clear into our 90s, so not only is building muscle after 50 in the cards, but building muscle after retirement is a go as well. So what’s the holdup?

The issue is aging, and the fact that while we’re young we often don’t have to work as hard to stay fit and recover quickly. Side effects of aging come on gradually, and muscle-building efforts need to increase along with it. Maintenance just won’t cut it: to build muscle we have to challenge ourselves to workouts that are hard to perform at first, and when that level is mastered, we have to go harder.

Octogenarian bodybuilder Ernestine Shepherd was interviewed by The Independent, and revealed that she didn’t start her targeted muscle-building efforts until she was 56 years old, and this was after a lifetime of no exercise and even being exempt from phys. ed. in school because of car accident injury she’d had as a child. Nevertheless Ernestine says that she went from being a receptionist (a sedentary job) to a professional bodybuilder, in better shape and with more energy in every new year. In 2010 she was declared the oldest competitive female bodybuilder by the Guinness Book of World Records.

If, like Ernestine you’re starting from scratch after 50, how do you begin? Read on for some starter tips.

Top tips for building muscle after 50.

The Top 7 Tips to Begin Building Muscle After 50

When a young man or woman decides to build muscle, it often takes no more effort than just trying. Some weight lifting, some cardio, and before these youngsters know it they’ve got muscle groups popping up in places they didn’t even know they had. But for older adults, building muscles is not just about losing weight and looking good, muscle gain starts to become vitally important to staying healthy and independent as we approach our 60s, 70s, 80s, and 90s.

As you age, not only do your joints creak and your hairs turn gray, but your muscle cells start to get eaten up and then not replaced. The younger we are, the more quickly the metabolic process revolves between catabolism (metabolism involving molecular breakdown to access energy) and anabolism (the metabolism of building new complex molecules like muscle proteins with that energy). When we get older, that process—along with so many others—slows down.

Reaching 50 is ideally the halfway point of a long and healthy life, and maintaining muscle strength is important if we want another strong 50 years on this earth. So without further ado, here are seven ways you can optimize your protein intake and start building muscle after 50.

1. Come to the Light

If you want to safely begin to build muscle after years of a largely sedentary lifestyle, you don’t want to head straight to the bench press. It’s not fun but it’s true: a twinge or a tweak to any one of your joints in these early days could snowball into a very severe injury if you’re not careful, derailing your efforts before you even really get going. You’ll get to the deadlifts and barbells soon enough after you’ve built up sufficient strength, but when starting out, start light.

Embracing lighter free weights can spur muscle growth without putting your wrist, elbow, and shoulder joints in any risk whatsoever. Studies show that more reps with lighter weights can stimulate protein synthesis just as well as lower amounts of reps with heavier weights. Lighter-weight training not only helps prevent initial injuries, but it also serves as a useful tool for repairing injuries. Similarly, higher reps with lighter weights leads to real muscle gain in older adults, so the only thing you’re losing out on is risk, not reward.

Once you build up a foundation of muscle, you and your joints will be strong enough to load up a barbell with ever-increasing weights, but as you begin, light is alright. Play to your strengths when it comes to strength training, and you’ll invariably improve as you age.

2. Stay on the Move

A sedentary lifestyle is dangerous to people at any age, but the damage done by inactivity compounds as we get older. To gain muscle, you have to not only incorporate a strength training program but also keep up with cardiovascular health. If your blood isn’t pumping well, you’re not getting the steady supply of oxygen and nutrients needed to build new protein for your muscles.

The cardio impact of walking and running changes in older adults, as seen in this 2010 study comparing younger (24 +/- 3 years) and older (64 +/- 6 years) participant groups. If you’re starting from scratch, begin with walking, increase to jogging and then treat yourself to new pair of running shoes, and know that you’re contributing to your muscle-building efforts with every new mile you cover.

3. HIIT Back

High-intensity interval training (HIIT) is a great way to burn calories and build muscle quickly for all ages and fitness levels. HIIT is characterized by alternating short bursts of intense physical activity with periods of rest, and according to the Mayo Clinic, it can particularly benefit seniors down to the cellular level, and even reverse certain symptoms of aging.

While experts don’t recommend that every workout be a HIIT workout, cycling it into your workout regimen can help push your abilities to higher heights. And if you’re in a HIIT class full of athletes, just remember that your high intensity is different from their high intensity, and that’s a-okay!

4. Rest to Recover and Rebuild

Regular exercise doesn’t mean constant exercise, and in fact research shows that rest days are just as valuable for muscle building as workout days are. Recovery time means rebuilding time for your muscles, while overtraining syndrome occurs when excessive exercise is paired with an inadequate amount of resting time. The results of overtraining come with side effects that disturb the body’s neurologic, endocrinologic, and immunologic processes, along with the unwelcome symptom of mood changes.

Your recovery times over 50 may be longer than they would be if you started working out in your 20s or 30s, but you’ll know your body best: rest as long as you need, and then get back at it with the gains you’ve made.

5. Stretch It Out

If your muscles are tight, it’s imperative that you stretch them. Stretching before (particularly dynamic stretches) and after your workout helps to limber up the muscle fibers and reduce the risk of muscle strains and sprains, whether you’re working out on your own or under the guidance of a personal trainer.

A full-body workout is not complete without stretching, so be sure to pencil it in, as increased flexibility can help you avoid injury and perform better in your workouts.

6. Good Things Come in Threes

Have you heard of the rule of thirds? It’s a photography guideline for visually pleasing picture compositions. Do you know what “omne trium perfectum” means? It’s Latin for “everything that comes in threes is perfect.” Those rules apply to your strength-training workout frequency too: 3 days a week is a perfect minimum.

While the more’s the better, especially if you’re diversifying your workouts (lift weights on one day, go for a run on the next, etc.), it’s nevertheless true that strength training at least 3 days a week can lead to good progression in muscle building and is a great place to start.

7. Feed Your Need

You cannot make muscles without protein. More specifically, you cannot synthesize new muscle protein without a proper amount of all nine essential amino acids. Most people looking to build muscle know that a high-protein diet and possibly consuming whey protein supplements will help them in gaining muscle, but just because you’re getting enough protein doesn’t necessarily mean you’re getting all the amino acids required to build lean muscle without your body cannibalizing the other muscle cells you have to supply the demand.

Research shows that consuming protein regularly throughout the day and especially after a workout helps stimulate muscle protein synthesis to its optimal degree in elderly people who are well advanced beyond age 50. To gain muscle while maintaining what you already have built, we recommend choosing a muscle-building protein supplement that has a full host of balanced amino acid content so you have all the ingredients you need to create new muscle.

You’ll Muscle Through

Building muscle mass is far from being a young person’s game: it’s everyone’s game to play and to win. While it’s important to start cautiously if you’ve never worked out before, it’s never too late to start building muscle, and the more you gain, the younger you’ll feel, as it’s been scientifically proven that proper fitness can reverse certain aspects of the aging process.

The health benefits of building muscle after 50 go far beyond improving your body weight and maintaining a trim physique. The strength-training efforts you start today can help you lose weight and, according to the American Bone Health organization, also help improve your bone density, which will matter more and more in the coming decades. Lifting weights or engaging in HIIT exercises 3 times a week could mean staying strong for the rest of your life.

Betaine Sources, Uses and Health Benefits

Betaine supplementation may help improve liver detoxification, heart health, digestive function, muscle building, body fat loss, and more. Find out how this amino acid derivative works.

Betaine is a methyl derivative of the amino acid glycine and can be found in food sources like sugar beets, spinach, shellfish, and wheat. As a methyl donor in chemical reactions within the body, betaine is important for liver and kidney health, and without it there can be fatty accumulation in the liver leading to serious cerebral, coronary, vascular, and hepatic diseases—dangerous consequences for your brain, your heart, your bloodstream, and your liver. With a sufficient amount of betaine you can protect your organs, improve certain cardiovascular risk factors, and increase your physical performance. For more about where betaine comes from and how it impacts your health, read on.

What Is Betaine? Where Does It Come From?

A naturally occurring amino acid derivative, betaine is also known as trimethylglycine (TMG). It’s a nonessential nutrient, meaning we don’t have to consume it to get it, as our normal functioning produces betaine as a byproduct of the nonessential amino acid glycine. However, beneficial amounts of betaine can be found in foods, including:

  • Sugar beets
  • Rye grain
  • Brown rice
  • Quinoa
  • Wheat bran
  • Sweet potato
  • Turkey breast
  • Beef
  • Veal
  • Spinach
  • Shellfish

Betaine was first discovered in the 19th century in sugar beets, which is where its common name is derived from. Its scientific name, trimethylglycine, describes its chemical composition: a glycine derivative attached to three (tri-) methyl groups on the molecular level. This is what gives it the ability to be a methyl donor (along with vitamin B12 and folic acid) when it comes in contact with other chemical compounds throughout the body. Methyl donation occurs in a process called methylation. The methylation process is crucial in protein function and many other critical actions in the body.

Betaine is also an organic osmolyte, a compound involved in the osmosis process, moving fluid into and out of cells to maintain fluid balance and prevent cell shrinkage or rupture. An imbalance there could lead to cell death.

The Health Benefits of Betaine

Betaine has long been a subject for scientific study in the realm of heart health and the prevention and treatment of heart disease, but more recently people have been taking betaine to enhance their exercise performance and improve their body composition as well. For more on how betaine can impact liver detoxification, heart health, digestive function, muscle building, and body fat loss, read on.

Betaine sources, uses, and health benefits.

1. Liver Function and Detoxification

Fatty acid buildup in the liver can lead to severe health consequences, including obesity, diabetes, and fatty liver disease. Fatty acids can accumulate due to dietary choices like eating too many sugary or fatty foods or consuming excessive amounts of alcohol. Liver buildup of fatty acids can cause abdominal pain, fluid retention, cardiovascular problems, and muscle wasting, not to mention damage and scarring to the liver. While the liver is one of our most resilient organs (able to heal itself in ways that our heart and our kidneys, for example, cannot), long-term damage and scarring can build up too, causing permanent damage and even liver failure or death.

The use of betaine treatments for hepatoprotection against conditions like fatty liver disease and nonalcoholic steatohepatitis has proven effective due to betaine’s ability to aid in recovery from liver damage and protect the liver from certain hepatotoxins like ethanol or carbon tetrachloride. Those toxins can find their way into our bodies through contact with pesticides, herbicides, and even some prescription medications. Detoxing them from the body without long-lasting liver damage is one of the top benefits we can all gain from betaine.

2. Heart Health

The cardiovascular benefits of betaine are the most thoroughly documented by researchers. By quickly and safely reducing the plasma homocysteine concentrations in our bloodstream, betaine protects us from homocystinuria, a condition characterized by high homocysteine levels that can lead to the development of arterial plaque and ultimately heart disease.

Betaine can lower homocysteine levels by providing homocysteine molecules with one of its three methyl groups, transforming homocysteine into the amino acid methionine, which is beneficially used in protein synthesis and liver cell protection against toxins, like in cases of acetaminophen (Tylenol) poisoning. Betaine has even gained Food and Drug Administration (FDA) approval for safe use in treating homocystinuria.

3. Digestive Aid

Our stomachs require a sufficient amount of stomach acid to digest the food we eat. If you have low stomach acid (a condition called hypochlorhydria), your food will only be partially digested, resulting in a lower absorption rate of the nutrients you consume. In some instances (as in the case of essential amino acids, vitamins, and minerals) we can only gain the necessary nutrients needed to live and function by consuming and then absorbing them. Absorption disorders can quickly lead to different forms of anemia, malnutrition, and wasting that detrimentally impact our health. Gastrointestinal overgrowth of Candida (a yeast bacteria) has been scientifically linked with lower levels of stomach acid.

The biggest component in stomach acid is hydrochloric acid (HCl), and an estimated half of individuals over 50 are not producing enough of it. Luckily betaine HCl, a combination of betaine and hydrochloride naturally found in beets, can work as an effective treatment for hypochlorhydria (a total absence of stomach acid). When taken as a supplement, betaine HCl increases the production of hydrochloric acid in the stomach, aiding digestion and enhancing the absorption levels of nutrients like iron, calcium, vitamin B12, and protein.

It should be noted, however, that betaine HCl should not be taken by those who have peptic ulcers, severe atrophic gastritis, or an inflammation of the stomach lining. While it used to be an over-the-counter drug often combined with vitamin B6, this form of betaine has since been banned (in 1993) from over-the-counter sale because it could not be recognized as “generally safe” by the FDA. It is now only available in supplement form, and because supplements are largely under-regulated, you should consult a health care professional for medical advice on the proper doses of betaine hydrochloride before taking it.

And while we’re on the subject, betaine hydrochloride should not be confused with betaine anhydrous, which is the FDA-approved form of betaine that is deemed safe and effective for treating high levels of homocysteine.

4. Muscle Building and Fat Loss

Due to betaine’s role in metabolizing protein, it has recently come into popular use as a workout supplement for muscle building and bodyweight management. Included in many pre-workout nutrient formulas, clinical trials have shown that betaine supplementation can help increase muscle power and endurance all while promoting the loss of dangerous body fat. This combination results in improved body composition for those who utilize betaine as a workout enhancement.

Be Better with Betaine

Betaine supplementation is not advised for children or pregnant or breastfeeding women. This is due not to any adverse side effects reported, but because of a lack of scientific evidence on the effects of high betaine levels in those populations. Likewise betaine hydrochloride can be dangerous for anyone with peptic ulcers or issues with their stomach lining, and should only be taken under a doctor’s approval.

However, as betaine is a naturally occurring compound in our bodies and vital for many important functions, it’s otherwise regarded as a safe way to protect your liver, enhance your physical performance, and help your heart. Consult with a medical professional if you have any hesitations, and find out what betaine supplementation could do for you.

How to Get the Best Amino Acids for Muscle Growth

Discover the important differences between BCAAs and EAAs for athletic performance, including the best amino acids for muscle growth, workout recovery, plus improved sleep, mood, energy, and fat metabolism.

Muscle protein turnover is a constant state of activity: repairing, replacing, and rebuilding every day. This is true for everyone, though for those who work out or do strenuous labor regularly, the rate is even faster. It’s also true that as we age, this process slows down, meaning the more we do and the older we get, the more support we need to maintain and grow our muscles. Those who hit the gym frequently have probably heard about amino acid supplements, but which are the best amino acids for muscle growth? Branched-chain aminos? The ones in creatine or whey protein? This article has the rundown on the amino acids responsible for muscle synthesis, and advice on how to get all the relevant amino acids for new muscle growth.

Branched-Chain vs. Essential Amino Acids

Branched-chain amino acid supplements (or BCAAs) are incredibly popular workout supplements among athletes and bodybuilders for their purported muscle-building abilities, but BCAAs are only a third of the essential amino acids (EAAs) needed to create new muscle. Here are the important differences when it comes to amino acids for working out.

Branched-Chain Amino Acids

BCAAs are taken as supplements to increase muscle gain, improve muscle recovery, and boost athletic performance. However, it’s a little more nuanced than that on the molecular level.

Branched-chain aminos are so-called because of their chemical structures, the branching chains of their chemical bonds. They are valine, leucine, and isoleucine, and they do indeed play vital and irreplaceable roles in muscle building.

BCAAs are metabolized in your muscles, not via the liver, which means they hit your bloodstream fast when you consume a BCAA supplement, and are especially useful for workout energy. Scientific studies show a link between BCAA consumption and improved glycogen energy storage, decreased workout fatigue, and greater muscle mass. So…what could possibly be the drawback?

The Issue with BCAA Supplements

BCAAs cannot work alone. This meta-analysis of the relevant research done over 30 years (between 1985-2017) found that there are no human studies that show BCAAs working independently to improve athletic performance or increase protein synthesis. While they definitely play a role in new muscle growth, they are not the magic bullet that many fitness enthusiasts are led to believe. How can that be so?

Well, the meta-analysis referenced above highlighted two distinct studies that both showed BCAA supplementation can actually decrease muscle protein synthesis when they are overabundant. As mentioned previously, it takes all nine of the essential amino acids to create new muscle, and without a sufficient amount of every EAA, the excessive amount of BCAAs in the body may accelerate the catabolic rate of muscles (catabolism being a destructive metabolism, the very thing most bodybuilders take supplements to guard against).

In two of the studies profiled, muscle tissue was being broken down much faster than it was being repaired due to the fact that the overwhelming amount of BCAAs in the subjects were seeking to complete their job: achieve protein synthesis. To do this they cannibalized muscle tissue to derive the other six essential amino acids that could not be found quickly enough anywhere else. It’s sort of like the way certain parasites kill their hosts, even though it’s an illogical action: molecules and basic organisms aren’t thinking about the bigger picture, they have one purpose and will clear a path of destruction to complete it if necessary.

Long story short, BCAAs cannot create new muscle alone, without all the ingredients necessary for new protein synthesis, they can actually work against your goals.

Other BCAA Concerns

BCAAs only work to improve muscle growth in those who just so happen to have a sufficient amount of the other essential amino acids in their bloodstreams. Too many BCAAs taken as a solo supplement can have some other negative side effects.

  • A too-high dose of BCAAs can interrupt serotonin production: Serotonin is one of your happy hormones, part of the group of chemicals like dopamine and your endorphins that keep you from feelings of depression and anxiety (among others). Serotonin is synthesized from tryptophan, which uses the same carrier as BCAAs to reach the brain. With extra BCAAs clogging the brain bus, tryptophan uptake decreases, and serotonin production declines.
  • Increased amounts of BCAAs lead to B vitamin depletion: The metabolic requirements of utilizing extra BCAAs includes using several B vitamins, which then leads to a B vitamin shortage. B vitamins are needed for a multitude of other bodily functions, and a deficiency in B vitamins can interrupt hormone production, nervous system functioning, and digestion.
  • Excessive BCAA concentrations can lead to blood sugar and insulin issues: Increased levels of BCAAs may be a predictor of type 2 diabetes onset, and are linked to a higher risk of insulin resistance.

The best amino acids for muscle growth.

Essential Amino Acids

The positive promises of branched-chain amino acid supplements can still be had, so long as you get them in proper balance with the rest of the essential aminos. The best supplements for muscle growth will include all of the amino acids you can’t make yourself, which includes those treasured BCAAs.

Essential vs. Nonessential Amino Acids

Amino acids are known as the building blocks of protein in the body, and have everything to do with muscle gain and protein synthesis. They also have a firm hand in our hormone production, our enzyme creation, our cognitive functioning, and our metabolism.

There are 20 main amino acids in the human body, and while 11 of them can be synthesized in-house and are deemed nonessential, 9 of them are essential to consume from outside the body (like plant and animal protein sources: fish, eggs, beans, etc.). Those nine essential aminos are:

  1. Valine (BCAA): Aids in energy production and stimulates muscle regeneration.
  2. Isoleucine (BCAA): Prevents muscle breakdown and is important in energy regulation and immune system activity.
  3. Leucine (BCAA): Vital in blood sugar regulation, growth hormone synthesis, and protein synthesis.
  4. Lysine: One of the amino acids for joint pain due to its role in collagen, elastin, and our connective tissues.
  5. Methionine: Supports liver function, heart health, and the processing and elimination of body fat.
  6. PhenylalanineHelps synthesize dopamine and norepinephrine, providing antidepressant and pain-killing effects.
  7. ThreonineAnother player in connective tissue (like lysine) and fat metabolism (like methionine).
  8. Tryptophan: The precursor for serotonin, important for appetite, mood, and healthy sleep.
  9. HistidinePrecursor to carnosine, which reduces lactic acid buildup and helps relieve muscle soreness.

Each of the essential amino acids plays a role in either muscle building, fat burning, energy creation, or joint health, or all of the above. Don’t stop at BCAAs when supplementing. Get the full deck of essential amino acids to truly improve your workout and increase your muscle growth.

Get the Essentials for Muscle Growth

To reiterate: BCAAs aren’t bad, they just aren’t the full package that amino acid supplements have to offer. They can’t build muscle all on their own, and too many BCAAs without the rest of their EAA cohort can have counterproductive or even destructive effects on your health.

A full roster of essential amino acids can aid muscle repair, improve exercise recovery, help suppress your appetite (due to the EAAs which work in the brain to regulate satiety and hunger hormones), improve cognitive function, aid weight loss, enhance metabolic processes, and lead to better sleep.

With EAAs, your post-workout recovery improves alongside your body weight, blood flow, lean muscle mass, and muscle strength. Add a complete, well-balanced EAA supplement to your sports nutrition regimen to get the very best of everything.

Amino Acid Pills vs. Powder: Which Is More Effective?

Amino acid pills vs. powdered supplements: why do you need amino acids, when do you need them, and which of these products works best? Discover the pros and cons of both delivery methods.

This article explores why you may need to take amino acid supplements, the difference between branched-chain amino acids and essential amino acids, plus the pros and cons of amino acid pills vs. powder supplements so you’ll know which one to choose for overall convenience and effectiveness.

Why Do You Need Amino Acids?

If you’re trying to lose weight or build muscle, amino acids could be the boost you’re waiting for. Why is that? Because while both can be accomplished with increased muscle mass, you cannot build muscle without all nine essential amino acids.

Your amino acids are the building blocks of protein, and protein is what you need for muscle growth. Essential amino acids (EAAs) are so-called because it’s essential that you ingest them—your body cannot make these amino acids on its own.

Your nine essential amino acids include: histidine, leucine, isoleucine, lysine, methionine, valine, phenylalanine, threonine, and tryptophan. Without the proper amount of each of one, you won’t get protein synthesis for new muscle no matter how hard you work out, because your body simply doesn’t have the ingredients. It’s sort of like trying to make a cake with everything but flour, or trying to put together a jigsaw puzzle with the corner and side pieces missing. You can try, but you won’t get the desired result no matter how much time and effort you put in.

The Difference Between EAAs, Branched-Chain Amino Acids, and Other Protein Supplements

Many protein powders and amino acid supplements contain handfuls of amino acids, often the branched-chain amino acids (BCAAs), which are valine, leucine, and isoleucine. For example, creatine is a type of protein found in dietary protein (animal meats) and produced by some of your nonessential amino acids, while whey protein contains all EAAs in one amount or another (though not always the optimal amount of each).

Taking these products as dietary supplements pre-, during, or post-workouts can help prevent muscle soreness, boost muscle protein synthesis, and aid in muscle recovery. They can even help prevent muscle tissue loss while you sleep. The fitness-minded often use casein protein supplements for just that, due to its slow digestion rate (though amino acid supplementation prevents catabolism while you sleep just as well, if not better).

People take amino acid supplements to prevent muscle damage during workouts, to repair and build new muscle, and to keep the muscle gains they’ve made even as they sleep.

Amino Acid Pills or Powder: Which Works Best?

So much of sports nutrition is counting, measuring, weighing, and timing: wouldn’t a pill or capsule be so much easier? Think about it: pre-workout, just take a pill; post-workout, just take another pill! It sounds almost too good to be true, and by the end of this in-depth explanation, you may agree that is indeed the case.

Let’s talk about the difference between powdered and pill forms of these essential nutrients, and which one works better for athletic performance, weight loss, and muscle building.

Amino acid pills vs. powders.

The Pros and Cons of Pre-Workout Amino Acid Pills

When deciding between amino acid pills and powders, use this pros and cons cheatsheet.

Pros

The upsides to pill or capsule EAA supplements are easy to imagine: they’re as simple to transport as vitamins, can be taken with minimal (if any) water requirements, and involve zero mixing. They’re time-savers, they’re convenient, and they come pre-measured. What could go wrong?

Cons

One of the biggest cons: proper dosages. The amount of capsules, soft gels, or pills you would have to take pre-workout to meet the amounts of amino acids used in clinical studies might not be as convenient as you think, especially if you’re supplementing as a professional athlete or bodybuilder. You just can’t fit 25 grams of protein into a half-gram pill.

Another con: the digestion time. A capsule or tablet has be to be digested once consumed, and not only does that require time and energy, but it also means that whatever fillers or gelatin that’s keeping the pill together is also getting ingested, when all you really want are your essential amino acids.

During particularly high-intensity workouts, it’s helpful to take EAAs before, during, and after workouts in different amounts, and it’s hard to get the timing right if you’re ingesting pills instead of powder. Not only that, all the time spent measuring powder isn’t avoided if you have to keep doing math on the dosage amounts of pills.

Long story short: some substances work well in pill form, like caffeine, but not so much a full host of essential amino acids.

The Pros and Cons of Pre-Workout Amino Acid Powder

Pros

Amino acid powders, whether you’re using a complete EAA supplement or a medley of different protein supplements, are faster acting, longer lasting, and don’t involve swallowing large, hard objects. Amino acid powder products can give you anywhere from 10-30 grams of active ingredients in one serving, and puts them to work ASAP as soon as you ingest them.

Cons

Those supplement powder containers can be awfully big sometimes, so much so that there have actually been multiple class-action lawsuits filed against some companies based on the size of their containers being too big for the product itself, with consumers finding them half or even a third full. You can’t be carting a container big enough to be a drum to the gym and back every day, nor is it always convenient to blend up a shake just before leaving the office to go work out. It would be nice to get the EAAs that can step up your lean muscle mass in pill form, but…the pros and cons weigh more heavily in the direction of choosing powdered supplements over pills.

Take A Powder…Literally

At the end of the day, creatine, whey, weight-gain, EAA, and BCAA supplements simply don’t work well in pill form; you just need so much more than a pill or capsule can deliver in the right window of time. It’s less a question of personal preference than it is a basic math equation. The powdered forms of these amino acid supplements are superior when it comes to all the key points of effectiveness, though it is fun to dream of a day when you can get perfectly enhanced exercise performance from one little pill.

Muscle Atrophy: Causes, Treatment and Prevention

Learn about what causes muscle wasting or muscle atrophy, and how best to prevent and treat this condition, including through the use of physical therapy, medical intervention, and staying active. 

Muscle atrophy is essentially muscle wasting: it’s what happens when your muscles waste away, frequently as a result of a lack of physical activity. This article will explore the causes and symptoms of muscle atrophy, as well as preventative steps people can take if they’re immobile or bedridden due to illness. Loss of muscle mass or muscle strength can be particularly devastating for those who are already in positions of compromised health, and so in an effort to help you maintain your quality of life, we’ve compiled the relevant information here.

Muscle Atrophy: Definition

Atrophy of the muscles occurs when a person is inactive for so long that their skeletal muscles (these are the muscles attached to your bones which literally make your skeleton move) begin to break down, and the muscle protein is cannibalized by the body. This can happen in small instances or large, catastrophic instances.

Muscle atrophy of the hand or forearm may occur if you spend weeks in a cast to heal a broken arm, which is why people in casts are given exercises to do while they’re immobilized to prevent protein degradation in their muscles and muscle wasting. Muscle atrophy of the legs or muscle atrophy of the thighs can happen on a much larger scale to those who become wheelchair-bound, either temporarily or due to becoming permanently paraplegic. In even more extreme cases, those who have been held as prisoners of war may have full-body muscle wasting due to confinement and malnutrition for significantly long periods, sometimes years.

Muscle atrophy is a decrease in muscle mass, either partial or complete, which is most commonly suffered when a person becomes disabled or their movements severely restricted. This makes it difficult or impossible to move the part of the body where the muscle has atrophied, and medical advice should be sought for solutions.

Muscle atrophy: causes, treatment, and prevention.

Muscle Atrophy: Causes

Significant decreases in activity levels can lead to muscle atrophy, and there are many situations where that can occur, causing what’s known as disuse atrophy. There are also instances of muscle atrophy due to medical conditions that inhibit the use of a body part, and even rarer causes like the muscle atrophy experienced by astronauts after relatively short periods (a few days) of weightlessness. Muscle atrophy in situations of being bedbound or ceasing intense physical training can come on in as little as 2 weeks. Some of the other causes of muscle atrophy are as follows.

  • Lack of physical activity
  • Advanced aging
  • Malnutrition
  • Stroke
  • Alcohol-associated myopathy
  • Burns
  • Temporary disabling injuries (broken bones, torn rotator cuff)
  • Permanently disabling injuries (severed spinal cord, peripheral nerve damage)
  • Prolonged corticosteroid therapy

Some of the diseases and medical conditions that can disrupt or restrict movement, thus leading to muscle atrophy, include:

  • Spinal muscular atrophy: A hereditary wasting disease of the limbs.
  • Osteoarthritis: Degeneration of bones and joint cartilage that leads to decreased movement.
  • Polymyositis: An inflammatory disease of the muscles.
  • Amyotrophic lateral sclerosis (ALS or Lou Gehrig’s disease): Compromises the nerve cells of the spinal cord.
  • Muscular dystrophy: A hereditary disease that causes muscle weakness.
  • Multiple sclerosis (MS): An autoimmune disease that destroys the protective sheathing of brain and spinal nerves.
  • Rheumatoid arthritis (RA): A chronic inflammatory disease of the joints.
  • Dermatomyositis: Inflammation of the skin and underlying muscle tissue.
  • Polio: A virus afflicting muscle tissue, which can lead to paralysis.
  • Cancer cachexia: The weight loss, lack of energy, and loss of appetite in someone undergoing cancer treatment.
  • Guillain-Barré syndrome: An autoimmune disease and form of polyneuritis, which leads to paralysis of the limbs.
  • Neuropathy: Nerve damage that results in loss of sensation or functioning.

Muscle Atrophy: Symptoms

Regardless of the cause, these are the symptoms that may alert you to possible muscle atrophy, after which a trusted medical professional should be sought for advice.

  • One of your limbs (arms, legs) appears markedly smaller than the other one.
  • You’ve spent a long time physically inactive (bedridden, hospitalized).
  • You’re experiencing noticeable weakness in one limb.

Not to be flippant about the subject, but there is some truth to the phrase “use it or lose it” when it comes to muscle. If you cannot move your muscles with regular physical activity, you will start to lose them.

Muscle atrophy pain may or may not be a symptom, as that depends on the cause of the atrophy. Many people will begin to lose muscle before they are aware it’s happening, and will have to rely on visual muscle size to realize they need medical attention.

Muscle Atrophy: Diagnosis

Once you’ve gotten in contact with a medical professional, the diagnosis may involve your full medical history, a review of any previous injuries, as well as an evaluation of your symptoms. Diagnosing the atrophy may also involve diagnosing the underlying medical condition, which may require blood tests, X-rays, MRIs, CTs, a nerve conduction study, or a muscle and/or nerve biopsy to find out what could be causing muscle atrophy if it’s not readily apparently (as it would be if you’d suddenly become bedbound).

Can Muscle Atrophy Be Reversed?

Depending on the cause, yes. There are some cases where a proper diet, exercise, and physical therapy can not only reverse muscle atrophy, but also prevent it from recurring. However, this will not be the case in some disease-related forms of atrophy, and it is important that you consult your doctor on what your expectations for muscle atrophy recovery should be in restimulating protein synthesis and rebuilding your muscles.

Muscle Atrophy: Treatment

Again, this will depend on the diagnosis of the cause, and also the severity of your muscle loss, but the treatments for reversible muscle atrophy may be as follows.

  • Physical therapy
  • Exercise
  • Ultrasound therapy
  • Dietary changes
  • Surgery
  • Electrical stimulation

If a lack of movement caused this condition, regaining movement will go a long way towards fixing it, and moderate exercise like walking, along with physical therapy, may be a way to regain muscle strength without needing surgery to fix skin, tendons, or ligaments too tight to begin moving again (as in cases of contracture deformity that could be caused by malnutrition or burn injury scar tissue).

Muscle Atrophy: Prevention

There are ways to prevent muscle atrophy before it happens, and ways to guard against it if you were fortunate enough to recover your musculature after one instance of muscle loss. If preventing muscle atrophy is in your control (and, of course, sometimes it will not be), here are a few ways to maintain muscle strength in adverse circumstances.

Stay Active

If you’re in recovery from a severe illness or have just come home from the hospital after a debilitating accident, it’s not as if you’ll take up jogging right away. However, movements as small as walking to your mailbox each day, or around the block, or up and down a single flight of stairs, can truly make the difference in the long run when it comes to maintaining your mobility.

Stay Nourished

Depending on your condition, this may be difficult, but when your body lacks the proper nutrition to stay running, it will start to catabolize your muscles for its needs, which is a form of self-cannibalization or destructive metabolism that literally eats away at your muscles. Make sure you’re getting proper protein, if not from whole foods, then in the forms of protein shakes or supplements, as every little bit may help.

In fact, supplementing with amino acids has been proven to help accelerate muscle recovery in times of sickness and illness and can help boost your muscle-building gains. To learn more about amino acid therapy for muscle atrophy, give this informative article, written by one of the world’s foremost amino acid researchers, a read.

Seek Physical Therapy

Physical therapy is particularly valuable for those with severe injury recovery (such as a car crash survivor) or a neurological condition, as therapists provide professional guidance on what, and how, and how often to stretch your body to build strength.

Try Passive Movement

Another way physical therapy can help you even before you have the strength to help yourself is with passive movement. Passive movement requires the therapist to gently move your legs and arms for you. This is how you can begin to recover from a very deep muscle deficit and build up strength and muscle again.

Preventative Measures

Not only will the above advice help prevent muscle atrophy, but it can also help discourage bedsores in those who are bedridden due to illness, and reduce the chances of developing dangerous blood clots in the limbs. Likewise, these movements may prevent muscle stiffness, retraction, and nerve damage. Consult a medical professional or licensed physical therapist for more advice.

Eliminate Atrophy

If you are in danger of muscle atrophy, take steps to make sure your protein intake and nutrients are sufficient, including the use of a supplement if necessary, like Amino Co.’s essential amino acid supplement, which contains all of the essential aminos required to build new muscle cells and structures. Also, make sure that you stay active, no matter in how small a way, to preserve your muscle function and prevent your muscles from falling into complete disuse. You cannot always control your body’s condition, but if the type of atrophy you fear is the type that’s preventable, it’s well worth the effort to maintain the quality of life and movement you’ve come to expect.

When Is the Best Time to Take Protein?

The best time to take protein supplements depends on your activity level, your personal goals, and the types of workouts you engage in. This article will provide you with specific, scientifically backed recommendations, and the reasoning behind that advice.

When taking protein supplements, people often wonder when exactly is the best time of day to consume them. Pre-workout? Post-workout? Is it okay to drink a protein shake before bed? Protein supplements can help people lose weight, build muscle, and recover from tissue damage due to injury or surgery. Because they’re so effective, most people want to be sure they’re utilizing protein the right way. So when is the best time to take protein? Short answer is: that depends on your health goals and the kinds of workouts you’re doing. For the longer answer and more detail, read on.

The Different Types of Protein Supplements

Protein is a source of energy for the body, essential for muscle growth, repairing damaged tissue, and preventing certain infections and diseases. Normal dietary protein comes from foods like meats, eggs, fish, dairy, grains, legumes, and seeds. Though animal products contain the most amount of protein, vegetables are sources of protein too, a fact well-known by those living a vegetarian or vegan lifestyle. Of the most popular protein powders on the market in fact, a significant portion are plant-based.

Plant-based proteins include:

  • Soy protein containing all nine essential amino acids.
  • Rice protein, which is lower in the essential amino acid lysine.
  • Pea protein, which has lower levels of the essential amino acid methionine and nonessential amino acid cysteine.
  • Hemp protein, which is low in lysine but high in fiber, and omega-3 and omega-6 fatty acids, both of which are essential, meaning your body can’t make them on its own, and needs to gain them from the foods you eat.

Dairy-based proteins include:

  • Whey protein, which is absorbed relatively quickly and contains all nine essential amino acids.
  • Casein protein from milk curds, also containing the essential amino acids, and with a slower digestion rate than whey (which is why people often take casein before they sleep, so it will digest throughout the night… more on that timing below).

Animal-based proteins include:

  • Egg protein powder made from pure egg white protein.
  • Creatine, which is not found in plants but can be synthetically created. Though it is an animal protein, depending on its origin source, it may nevertheless be possible for vegans to use creatine as a supplement.

These are among the most commonly known protein powders available to buy, but we here at the Amino Co. have also developed an essential amino acid (EAA) blend that isn’t lacking or low on any of the amino acids required for protein synthesis and new muscle growth. It also blends free-form amino acids with whey protein and creatine, a nonessential protein that nevertheless has great value as a supplement. These forms of protein are used to help those who want to build muscle rapidly, and can even benefit those with muscle, neurological, or neuromuscular diseases.

The Varied Uses of Protein Supplementation

From muscle building to weight loss, here’s a quick look at all that supplemental protein can do to benefit your body.

Exercise Performance and Recovery

Added protein has been shown to increase endurance during training and workouts, as well as reduce soreness and speed up post-workout recovery. The timing of your protein intake matters here, whether you’re eating high-protein foods or taking supplements. Read on to learn about workout-specific timing recommendations.

Muscle Building

Muscles can only be built when you have the proper amount of amino acids for protein synthesis, and when you’re consuming more protein than your body breaks down during workouts. Taking a protein supplement, especially one that contains all the necessary EAAs for muscle growth, can make a huge difference. Finding the right anabolic window, the period of time when the protein you take in will go directly to your muscles, is something the International Society of Sports Nutrition has done extensive research on, and we, too, will provide specific scientific reasoning below.

Muscle Loss Prevention

Muscle mass is lost not only during intensive workouts, but also naturally as we age. Each decade you live after the age of 30 brings with it a higher risk of losing muscle (anywhere between 3-8% per decade). Proper protein intake is not only valuable to athletes, bodybuilders, and anyone who works out regularly, but it’s also important for each and every one of us as we age. Most Americans reserve their protein more for dinner than breakfast (3 times the amount on average is the difference between the two meals), and could use a supplemental boost of protein first thing in the morning to shore up their protein stores and help prevent the loss of muscle mass due to aging.

Fat Loss Facilitation

Protein is filling enough to help curb hunger pangs and chemically contributes to appetite suppression by reducing the “hunger hormone” ghrelin. A high-protein diet raises your metabolism and increases levels of appetite-reducing hormones like peptide YY (PYY) and glucagon-like peptide-1 (GLP-1). More satiety means fewer calories consumed throughout the day, which quickly leads to safe, maintainable weight loss and the reduction of dangerous body fat.

The Enduring Power of Protein

Popular because they’re convenient and effective, protein powders and supplements are here to stay and can offer you a wide variety of options, from self-mix formulas and powders to ready-to-drink protein shakes. If you’ve got your preferred protein supplement ready to go, then it’s time to wonder: when should you drink protein?

The Best Time to Take Protein Depending on Your Workout

Depending on your goals and activities, there are recommended times to take protein for the greatest effectiveness for your energy levels and muscle-building needs. Here are specific recommendations based on different types of workout activity.

The best time to take protein supplements.

Aerobic/Cardiovascular Exercise

Best time to take protein: Pre-workout and post-workout

The amino acid leucine is one of the three branched-chain amino acids (BCAAs), and it promotes muscle recovery after workouts. Not only that, it activates protein synthesis, prompting new muscle to be built. One might think that due to leucine’s ability to boost endurance and stamina, one should take a BCAA supplement before a workout, but the science contradicts that idea. Not only are BCAAs only three of the nine essential amino acids needed to construct new muscle, leucine and the other BCAAs (isoleucine and valine) experience oxidative degradation during aerobic activity.

BCAAs are Insufficient Pre-Workout

Adding these limited amino acids before your workout, especially in the unbalanced form of BCAAs instead of a complete EAA formula, means that a greater percentage will be oxidized and used for energy instead of muscle building. Your body does not want to be out of balance, so a sudden overabundance of a few amino acids will cause the body to clean up and reduce them in order to maintain equilibrium.

Rather than risk burning off the protein you put in because your body is only looking for energy sources, it’s better to take a full measure of EAAs within the hour after your aerobic workout, when your body is looking for supplies to rebuild. Leucine will be there to prompt muscle protein synthesis, and the rest of the essential amino acids will all be included in the ideal ratio for generating new muscle growth.

EAAs are Effective Pre- and Post-Workout

That being said, taking a complete amino acid protein supplement before an aerobic cardiovascular workout (like a high-intensity interval training or HIIT class), not only provides the necessary ingredients for muscle building, but also helps fight fatigue in a way that only taking BCAAs can’t, by fueling your body with the amino acids that help produce dopamine and serotonin in the brain.

Whether you’re walking, cycling, running stairs, or jumping rope, start by taking your EAA supplement 30 minutes before your workout session. The biggest benefit comes when you take your EAA supplement within an hour after your workout, when your blood flow is strong and active. Not only will the amino acids rush in to replace damaged muscle fibers with new muscle, EAAs can also help calm unnecessary inflammation. That will help quicken your recovery, allowing you to feel only the good side effects of working out, like increased energy and light euphoria, instead of soreness and fatigue.

Resistance Exercise

Best time to take protein: Pre-workout, during, and post-workout

Research has shown that EAAs given 30 minutes before a resistance exercise workout prompt muscle protein synthesis much more effectively than consuming EAAs afterwards does. Taking a protein supplement before this type of workout helps prevent the breakdown of muscle protein during the activity, and also increases blood flow to the muscles, thus getting the amino acids quickly into the muscle where they’re needed.

Consuming EAAs after a resistance workout is not harmful by any means, as that method, too, will prompt the stimulation of muscle protein synthesis, but it’s not ideal to leave the consumption of EAAs until after your resistance training is complete. Our recommendation is to first and foremost take a complete protein supplement before a resistance workout, and if possible take them throughout and/or after as well to get the most benefit.

Bodybuilding

Best time to take protein: Pre- and post-workout, and also before bed.

Immediately before and after a weight-lifting workout, we recommend that you take 15 grams of EAAs each. An EAA supplement has been shown to have a faster effect on muscle protein synthesis than either whey or casein protein alone. However, our Amino Co. blend of free-form EAAs with whey and creatine support ensures that you get a fast dose of EAAs and that the EAAs from whey will digest more slowly as you work out, offering a steady supply to help prevent muscle breakdown. Creatine helps prevent catabolism by supplying faster energy than your body can naturally generate from muscle cell mitochondria. This means more energy for more reps, which ultimately means more work put in and more muscle gained.

An hour after your post-workout dose of EAAs, we recommend another 15-gram dose. On off days, continue taking these same doses, measured between meals instead of surrounding your workout. Lastly, it’s also recommended you take another 15-gram dose before bed to keep your muscles fed as you sleep and to help prevent muscle breakdown as much as possible. You work hard to gain your muscles, and we encourage you to protect those gains at every opportunity. Set your alarm to take one more dose around 4 am if you know you won’t have a problem falling back to sleep, that way your muscles never go hungry for fuel.

It should be noted here that bodybuilders aren’t the only ones who benefit from taking extra protein before bed. One study of 16 elderly men showed that those who consumed casein protein (which digests slowly) before bed had increased muscle growth over those who took a placebo, despite being less active individuals. When you’re sleeping, it’s the protein that counts, and not the activity.

Is There Any Downside to Taking Protein Supplements?

The majority of scientific studies into how our bodies process high amounts of protein show that you can safely consume plenty of protein without risk of harmful side effects. Unless your doctor advises against protein supplements or you have a known kidney issue like rhabdomyolysis, there is no need to worry about excessive protein intake; merely take your products as recommended and spread them throughout your day.

Timing Is Everything

At the end of the day, it’s true that people who work out need more protein, but even those with a less active lifestyle benefit from consuming extra protein for strength, for maintaining healthy weight levels, and for preventing the loss of muscle mass we all experience as we age.

Make a protein shake for breakfast, have another to curb your appetite between meals, and make another as a beneficial treat before bed. Know that the more regularly you take in balanced forms of protein like Amino Co.’s complete EAA blend, the more good you can do for your body. Whether you’re working out or not, upping your daily protein intake is safe and smart. Bulk up, slim down, and stay strong with protein!

BCAA vs. Creatine: What You Need to Know

BCAA vs. creatine: a comprehensive look to help you decide which you should choose, or whether you’d rather utilize a product that combines the two supplements for better energy, muscle strength, and protein synthesis.

If you spend enough time in the gym, you will eventually run across this question: BCAA vs. creatine, which supplement do you prefer? Before you can answer that question, you’ll need the information behind both BCAAs and creatine: what are they? What are the upsides and downsides to each? How can they help build muscle? Can they both be taken together? You’ll find the answers to all of those questions here, plus learn about the one ultimate supplement that perfectly marries the two together, so you never have to compromise for imbalance in your muscle-building nutrients.

BCAA vs. creatine: a comprehensive look.

What Is BCAA? What Is Creatine?

We’ll start with the definitions, and then move on to the differences between these two supplement options.

BCAA: Branched-Chain Amino Acids

A BCAA supplement is made up of branched-chain amino acids, specifically the three amino acids leucine, isoleucine, and valine. There are a total of nine essential amino acids, essential because you must eat or otherwise consume them to get them (other amino acids are produced in-house by your body). Leucine, valine, and isoleucine are essential amino acids.

“Branched-chain” refers to the molecular structure of these three specific amino acids. The chemical bonds branch off of the main structure.

Studies have shown that BCAAs help reduce muscle damage and soreness in post-workout recovery.

While it’s possible to get a sufficient amount of the BCAAs from your diet, for those who work out intensively, and/or for those on specific diets aimed to lose weight, it might be difficult to get the right amino acid balance, which is why some will chose a BCAA supplement in the hope that it will round out their nutrients. However, it should be noted here that muscle synthesis cannot take place without all nine essential amino acids, so a complete essential amino acid (EAA) supplement is preferable to a BCAA one—you cannot build muscle with only a third of the necessary ingredients.

To cut calories without having a negative impact on protein intake for muscle mass is important, and BCAAs are often taken to try to ensure there’s no interruption to protein synthesis while dieting. Even if weight loss isn’t your goal, the BCAAs gained from taking a complete EAA supplement might still help in that department by contributing to appetite control.

BCAAs have similar benefits to a whey protein shake, but with fewer calories. Moreover, the amino acid leucine is one of the two specifically ketogenic amino acids, another way that BCAA supplements contribute to fat loss (the ketogenic diet is all about burning off fat, and doing it both quickly and safely).

BCAA supplements are perhaps best suited for CrossFitters, bodybuilders, or rowers, but again, they are only a third of the essential amino acids, all of which are necessary for muscle building.

BCAA Quick Facts

  • BCAAs provide three of the nine essential amino acid building blocks of muscle tissue.
  • BCAAs help protect lean muscle and guard against muscle wasting.
  • BCAA supplements are a source of longer-term energy, and can help reduce exercise fatigue.
  • BCAAs help promote fat loss via appetite suppression and increased metabolism for burning calories.
  • BCAA supplements provide higher strength gains than whey protein does.
  • There are no harmful side effects reported from BCAA supplementation.

Creatine: The Energy Protein

Creatine is creatine monohydrate, the protein found in animal sources of meat like fish, poultry, pork, and red meat. Creatine contains two different amino acids, arginine and methionine, of which methionine is essential.

Unlike the weight-loss potential in BCAA supplements, taking creatine can lead to initial weight gain, as it causes some water retention in the muscles. Likewise, if you’re not drinking enough water while taking creatine, cramping can occur, meaning it’s more important than ever to stay hydrated while working out.

Researchers have stated that creatine might help lessen the effects of osteoarthritis, slowing the loss of bone mass as you age. Another unique benefit of creatine is its ability to deliver the rapid energy that is needed during fast muscle contractions (when sprinting, for example). That means creatine gives you longer endurance, which means more reps, which means more muscle growth. This is why creatine is best suggested for powerlifters or sprinters, and why it’s a part of our unique EAA blend (see below for further details).

Creatine Quick Facts

  • Creatine breaks down into phosphocreatine (CP), which provides rapid energy for muscle contractions.
  • Creatine causes the release of the anabolic hormone IGF-1, used in promoting muscle growth.
  • Creatine is a quick source of muscle energy, allowing for more reps.
  • Creatine use aids long-term bone strength for weight trainers.
  • Creatine increases strength during resistance training by up to 20%.
  • Some water retention and cramping is reported with the use of creatine, but the effects are short term.

BCAA vs. Creatine: Which Should You Use?

If you’re here to make a choice, now’s the time to review your fitness goals and how each of these products might influence them. Research suggests that BCAAs help to increase muscle mass for those doing resistance training. If your diet is low on protein intake, say if you’re vegetarian or vegan, BCAA supplements are a great way to promote muscle protein synthesis, but remember that they are also only a partial supply of the amino acids you need for muscle building.

Likewise, a study also showed that muscle strength increased up to 8% for those using a creatine supplement while resistance training. Creatine can provide rapid energy when the usual muscle cell energy supply of adenosine triphosphate (ATP) is slow to regenerate, and it goes a long way towards the kind of strength building and increase to muscular force that might be preferred by powerlifters.

Both supplements aid muscle recovery, both contain at least one essential amino acid, both help drive protein synthesis, both of them are good to take as pre-workout supplements for their benefits, and honestly, unless you have a specific reason to not take one of them, you may be thinking that you want to take both. Well good news for you then, because you can! In fact, we recommend that you do.

BCAA and Creatine Together

You may have noticed that there was no overlap between the amino acids from BCAA supplements and creatine supplements, which means taking both will not overdose you on any one amino acid. Rather than think of them as enemies in some competition for supplement supremacy, BCAAs and creatine can be two valuable players on the same team: your team. Nothing bad will happen to you if you combine them (they’re not baking soda and vinegar in a third grader’s science fair volcano or anything), and since they both aid sports performance, boost muscle building, help with fat loss, and ease muscle recovery, when taken together you may see improved results in all of those categories.

However, if you’re after a full roster of the essential amino acids, there are amino acid supplements that include all three BCAAs, plus the other muscle-building EAAs. Whether you’re looking into supplementation because you’re lifting weights or attempting to lose body fat or both, a protein powder with only partial, unbalanced amounts of amino acids just won’t do the trick.

A Complete EAA Blend

When it comes to muscle-building supplements, our blended EAA formula not only contains eight of the nine essential amino acids, including the BCAAs, but it also supplies them with the energy of creatine and the steady amino acid digestion that comes from whey protein supplements (derived from milk).

This supplement is scientifically proven to increase human muscle growth and can help prevent muscle breakdown in the elderly. It was also designed to contain the exact ratio of amino acids needed to build muscles without overtaxing your body with excessive or unnecessary amounts of any one.

When building muscle, you don’t want to show up with a partial supply of the building blocks of protein. Instead, you want a comprehensive EAA supplement that helps all the work you do weight training at the gym to pay off. Instead of a dose of BCAAs here or a dash of creatine there, we recommend you get the most out of all of the above with our combination of EAAs with creatine and whey protein support. If the question is BCAA vs. creatine, the real answer is the Amino Company’s blends: for balance, for building, for the best of both worlds and more.

Most Popular Supplements for Muscle Growth

Learn the chemistry behind the traditional top supplements for muscle growth, and find out about the newest and most comprehensive supplement that’s about to revolutionize muscle building.

If you’re looking for supplements for muscle growth, you’ve probably already noticed that it’s a pretty crowded field. Different proteins and combinations and timing strategies get discussed, and before you know it you feel like you need about half a degree in chemistry just to build muscle at the gym! We’re streamlining the relevant information on muscle-building supplements, their pros and cons, so you can decide on the best supplements for your own fitness goals. If you’re in a rush, skip to the end, because there’s a new supplemental option that combines the best muscle growth nutrients you’ve ever known, all in one complete, balanced formula that will best all the rest. Read through to learn about the ideal muscle-building combo, a powerful protein trinity.

The First Steps Towards Muscle Building

Getting the most out of your workout involves taking a few first steps before you can start targeting muscle gain specifically. The first steps after taking up regular exercise are:

While supplements are not mandatory to reach these goals, they can be excellent aids to quicken your progress and maximize your protein intake without bringing unpredictable calories to your diet. Next up we’ll discuss the top supplements for muscle growth that you can choose from when attempting to gain muscle mass, and reveal a cutting-edge, scientifically-backed newcomer to the muscle-building supplement world.

Traditional Top Supplements for Muscle Growth

Over and above eating well and lifting weights, here are some protein and muscle-building supplements you can use to augment your workout goals, some of them more effective than others.

Top supplements for muscle growth and bodybuilding.

Carnitine

Carnitine is the general term for a group of amino acid compounds that include L-carnitine, acetyl-L-carnitine, and propionyl-L-carnitine. Carnitine is a transporter that moves long-chain fatty acids into mitochondria, where they’re oxidized or burned for energy.

A popular supplement for fat-loss, carnitine can also aid muscle growth by increasing blood flow to muscles, lessening muscle soreness, and increasing nitric oxide production, all of which improve your post-workout recovery. The combination of these benefits makes carnitine a strong asset for energy-boosting while you’re building muscles through exercise, especially when utilized in pre-workout and post-workout shakes. Though it doesn’t directly contribute to muscle building, it does provide valuable energy assistance, and improves performance during endurance athletics.

Pros

  • Aids athletic endurance by providing energy transport.
  • Helps ease muscle soreness and improve post-workout recovery.

Cons

  • Does not directly increase muscle, but instead aids in workout energy.
  • Carnitine is only a peripheral aid to individuals working to build muscle via exercise.
  • Carnitine would need to be taken alongside direct protein or amino acid supplements to be most effective.

Whey Protein Powder

A milk protein derived from whey, which is the watery part of milk that separates from the curd, whey protein is an excellent supplement affecting protein synthesis. With a high level of branched-chain amino acids or BCAAs, and including some amount of all nine essential amino acids (EAAs), this protein supplement digests relatively quickly and can help with rapid muscle building.

Whey protein can help increase blood flow due to its content of peptides, and is regularly consumed by bodybuilders immediately after their training sessions (within the hour). When choosing a whey protein, it’s recommended that you find a powder containing whey protein hydrolysates, which are proteins broken down for faster digestion.

Pros

  • Whey protein is a complete protein, containing all nine essential amino acids.
  • Whey protein is high in the branched-chain amino acids (BCAAs).

Cons

  • While whey protein is a fast-absorbing whole protein, free-form amino acids can be absorbed much more quickly.
  • Whey protein’s amino acid content is not optimally balanced, and a properly formulated essential amino acid supplement can have 3 times the effectiveness rate as a whey protein powder supplement alone.

Glutamine

Glutamine is an amino acid that not only helps build muscles by increasing the levels of the essential amino acid leucine in muscle fibers, but it also helps fight against muscle breakdown, and has been shown to play a significant role in protein synthesis.

Incidentally, glutamine can also be recommended for those with digestion issues (diarrhea or constipation), anxiety, cravings for sugar and/or alcohol, and those with poor wound healing.

Pros

  • Valuable as a precursor to the essential amino acid leucine.

Cons

  • Glutamine aids only one of the nine essential amino acids needed for muscle building, and so is far from being the most effective muscle-building supplement.
  • Glutamine is unnecessary if you’re taking a complete blend of essential amino acids.

Casein Protein Powder

Casein is the other milk protein that is derived from the curd of the milk and not the whey. Casein has a slower digestion rate than whey protein does, which makes it an excellent protein to take before bed, as it digests while you sleep and helps to prevent catabolism (which is to say destructive metabolism, a kind of self-cannibalism the body sometimes resorts to for energy).

Because increased calorie intake is also needed to build muscle, casein can help by being less filling than whey, allowing you to consume more alongside it. However, it’s also suggested that taking a combination of whey (or better yet free-form essential amino acids…read on!) and casein after a workout can help with muscle protein synthesis better than taking either one of them alone. Be advised that a casein protein product with micellar casein is the slowest-digesting form of casein readily available, and is your best bet when buying it as a supplement.

Pros

  • Casein protein has a slower digestion rate than whey, which can help prevent catabolism during sleep.

Cons

  • Works best when combined with stronger protein supplements like whey protein or free-form essential amino acids.

Beta-Alanine and Carnosine

Beta-alanine, an amino acid and key component of the dipeptide carnosine, aids in increasing carnosine levels and thus heightening muscle strength and muscle endurance. Higher levels of carnosine also increase the force of muscle contractions, and combining it with creatine (next on the list) has the greatest effect on losing body fat and gaining lean tissue, as was seen when the two were studied during a 10-week resistance training program conducted with collegiate football players.

Pros

  • Carnosine contributes to muscle endurance, leading to more powerful workouts, which can then translate to increased muscle.

Cons

  • Carnosine does not directly build muscle, but instead helps aid in workout endurance.
  • Carnosine is most effective in combination with proteins like creatine or free-form amino acids, and so is best as peripheral support for muscle building.

Creatine

Popularized as a workout supplement in the 1970s, creatine is made up of three amino acids—glycine, arginine, and methionine—and is vital for supplying the energy for muscular contraction. Creatine can be found in the forms reatine alpha-ketoglutarate (AKG), creatine monohydrate, and creatine malate. Creatine has been shown to increase the levels of insulin-like growth factor-1 (IGF-1) in resistance-exercise training, which is essential for stimulating muscle growth.

Creatine is converted to phosphocreatine (CP) in the body, which then provides energy for explosive exertions like heavy weight lifting or sprinting. The creatine-phosphocreatine system provides an increase in energy supplied to muscle cells when your body is using more ATP (adenosine triphosphate) than is being regenerated in the cells’ mitochondria. This increases your athletic endurance.

Pros

  • Provides energy for increased exercise performance, especially when you’re using more ATP than the mitochondria of your muscle cells can regenerate.
  • Creatine helps stimulate muscle growth.

Cons

  • Creatine is not most effective when taken alone, but is instead at its best when paired with an essential amino acid (EAA) supplement, where it will help provide the energy needed for increased muscle protein synthesis.

Nitric Oxide Boosters (Arginine)

Nitric oxide (NO) in the body serves to dilate blood vessels, thus allowing better blood flow to muscles, providing them with energy, nutrients, water, anabolic hormones, and oxygen—everything your muscles need to function, grow, and thrive. Nitric oxide boosters do not contain nitric oxide, but instead provide it via the amino acid arginine, which the body converts into nitric oxide.

Arginine supplements are often marketed based on their association with muscle growth, increased muscle strength, and loss of bodyweight. However, we recommend supplementing with citrulline to increase arginine, as arginine supplements don’t produce significant increases in blood arginine concentrations due to the liver‘s effectiveness at clearing absorbed arginine. Citrulline, on the other hand, is converted into arginine by the kidneys, and the arginine is then released into the bloodstream; this more effectively increases your arginine levels. Additionally, there are no adverse effects associated with citrulline supplementation, while arginine consumption can sometimes lead to gastrointestinal discomfort.

Pros

  • Arginine in the bloodstream leads to more readily available amounts of nitric oxide, essential for muscle functioning.

Cons

  • Counterintuitively, arginine supplements are often ineffective at supplying useable arginine to the bloodstream.
  • Instead citrulline is recommended to supplement for an effective increase in arginine, and can be taken alongside or included in EAA and protein supplements for optimal muscle performance.

ZMA (Zinc, Magnesium Aspartate, Vitamin B6)

Supplementing the minerals zinc and magnesium aspartate along with vitamin B6 is sometimes important to bodybuilders because they become depleted during intense training and need to be specifically replaced. These nutrients are necessary for maintaining proper sleep and hormone levels, as testosterone particularly can be compromised by intensive training.

Athletes who take ZMA have been shown to have increased levels of IGF-1 and testosterone, both of which have an influence on muscle gains. ZMA is recommended to be taken before bed on an empty stomach, to allow for better uptake and to help improve sleep quality and the muscle recovery that sleep provides.

Pros

  • Can help correct vitamin and mineral deficiency caused by intensive weight training.

Cons

  • ZMA supplementation does not lead to direct muscle growth, but can be taken as needed alongside free-form amino acids or traditional protein contributions like whey or creatine, depending on your workout style and your body’s needs.
  • Not everyone will need the extra supplementation of ZMA.

HMB (Beta-hydroxy beta-methylbutyrate)

Beta-hydroxy beta-methylbutyrate or HMB is a molecule derived from the processing of the essential amino acid leucine, and helps protect against muscle protein breakdown. HMB is often recommended only for those who are beginning weight-training exercises, as the scientific results seen in those who are more experienced with muscle training are less significant. This is due to the fact that HMB is heavily reliant on a steady and abundant supply of EAAs to be effective. When the EAA supply dips down, so does the effectiveness of HMB; it cannot work alone.

Pros

  • HMB supplementation can be good for resisting extreme catabolic states, such as in individuals with critical wasting illnesses.

Cons

  • HMB without an excess supply of EAAs is only marginally effective.
  • EAA supplementation is also needed to derive maximum benefits from HMB supplementation.

Branched-Chain Amino Acids (BCAAs)

The branched-chain amino acids are a subcategory of essential amino acids, and are designated by the molecular structure of leucine, isoleucine, and valine. BCAAs make up 14% of the amino acids that reside in your muscles, and it’s been shown that taking a supplement of BCAAs during resistance-training exercise increases muscle strength, fat loss, and lean mass.

However, while research shows that leucine in particular stimulates muscle protein synthesis, and that together these three amino acids diminish cortisol (a catabolic hormone), increase energy, and reduce delayed-onset muscle soreness, BCAAs when consumed alone are not fully effective. All nine essential amino acids are needed to make new muscle, and in fact, the the rate of muscle protein synthesis is directly affected by the availability of all your essential amino acids—the more you have, the faster your rate of muscle synthesis, and the fewer you have, the slower the rate. Because of this, research actually shows that BCAAs when taken alone have little to no effect on the rate of muscle protein synthesis in humans.

Pros

  • BCAAs are valuable amino acids that can be taken to help some aspects of muscle building.

Cons

  • BCAAs are only three of the nine essential amino acids, and all essentials are needed to create new muscle.
  • BCAAs have little to no effect on muscle protein synthesis when taken alone.

An Essential Amino Acid (EAA) Blend: The New Top Muscle Growth Supplement

If BCAAs ever sounded good, you’ll probably be more interested in a complete EAA supplement. Our unique EAA supplement is an ideally proportioned blend that combines the strengths of whey protein, creatine, and the eight essential amino acids that contribute directly to muscle growth. With our EAA blend, you’ll not only get the BCAAs mentioned above, but also a full cocktail essential amino acid supplement. It contains the key factors that make whey protein and creatine effective too, giving you the best of every top effective traditional supplement on the market.

EAAs and Muscle Protein Synthesis

The human body is made up of about 20% protein, and amino acids are used to form our muscles, tissues, and organs (not to mention the hormones needed for cognitive and physiological function). The key to our muscle-building product that helps make it more effective than other supplements, and even some dietary sources of essential amino acids, is its absorption rate and digestibility.

The EAAs derived from dietary proteins have to be digested first and then absorbed, while free-form amino acids are absorbed more quickly and completely. With eight of the nine essential amino acids (minus tryptophan which is not necessary to supplement for muscle protein synthesis), the amounts of EAAs are maximized more than any naturally occurring protein can deliver.

EAAs with Whey Protein’s Support

While free-form EAAs provide faster absorption, an intact protein like whey provides for a longer absorption period, sustaining the supply of EAAs after the rapid absorption of the free-form EAAs. Designed to work in concert with one another, our muscle-growth supplement combines its EAA profile with a balanced inclusion of whey protein for steady, ongoing support of muscle protein synthesis.

EAAs and Creatine’s Energy

Because creatine-phosphate provides the energy for sudden bursts of physical activity like lifting heavy weights or sprinting, it’s included in the Amino Co.’s technology to provide the energy needed to convert EAAs into muscle via muscle protein synthesis. Instead of waiting for the mitochondria of muscle cells to metabolize ATP for energy, creatine covers the time gap when needed, completing the full circle required for ideal muscle building: the rapid essential ingredients, the long-haul supply, and the energy to put them to use.

The Amino Company Advantage

Our product is a unique, patent-pending blend of essential amino acids, whey protein, and creatine that outperforms all other supplements in increasing muscle mass. Good for increasing strength in the elderly and easy to include in drinks or smoothies, Amino Co. supplements are scientifically proven to be effective in muscle protein synthesis over any other supplement, food, or protein choice currently available.

The ABCs of Muscle Growth

On a first glance at muscle growth supplements, it looks like an alphabet soup of vitamins and molecules and chemistry notes, but the more knowledgeable you become about your own body’s strengths and needs, the closer you’ll approach a PhD’s level of understanding when it comes to which supplements best support your goals. Effectiveness is key, bolstered by practical results that can be not only felt, but also scientifically proven. In the end, you can see which supplement brings you the greatest value.

The strongest performers from the traditional list of muscle growth supplements have been brought forward to the new frontier: an EAA blend that brings the best of everything essential to building and maintaining new muscle. The Amino Company provides the full circle of quick, long-lasting, and energized EAAs for muscle building. When you take our unique blend, you’re guaranteed to have an optimally balanced formula designed specifically for human muscle growth (and not lab animals). With the Amino Co. on your team, you can reach higher heights of strength faster and more effectively than ever before!

How Amino Acids Support Female Muscle Growth

Is it truly more challenging for women to build muscle? To answer that question, we first separate the myths about gender differences and muscle growth from the actual science. Then, we offer tips everyone can use to get serious muscle growth results.

Female muscle growth. It’s not a phrase you hear too often. However, whether you’re a man or a woman, muscle building benefits your overall health and well-being. Strong scientific evidence shows that increasing your lean muscle mass can help you stay healthy as you age, support fat loss by keeping your metabolism running at full capacity and prevent the development of chronic diseases.

If you’re born male, you’re coached from a young age to want to grow up to be big and strong. But if you’re born female, you receive the opposite message. With the emergence of ripped and toned female fitness influencers taking social media by storm, the tides appear to be shifting. Nonetheless, society still tends to instruct girls to train themselves to be as dainty as possible—in part, so they can grow up to be women who attract big, strong men.

But the health benefits of muscle mass apply to everyone, regardless of gender. However, it can be more challenging for women to build muscle for a variety of reasons.

In this article, we’ll explore the scientific realities behind the common belief that muscle building comes more naturally to men than to women. Plus, we’ll offer tips that everyone can use to increase their physical strength and get serious muscle growth results.

Do Men Build Muscle More Easily Than Women?

If you’re at all familiar with the resources out there for people interested in muscle building, you’ve probably noticed that the vast majority of it is written by male authors for male audiences. While that has begun to shift somewhat as more women get into powerlifting, bodybuilding, and sports science, these realms are still dominated by men.

In those realms, a concept that many take for granted is that muscle gains come more easily for men than for women. This concept is propped up by claims that men and women have significant physiological differences that give men an advantage when it comes to physical strength and performance.

 

How amino acids can maximize female muscle growth.

What Science Tells Us About the Differences Between Men and Women

Let’s begin by comparing the average metabolic rates—the calories you burn just by going about your day—for men and women. According to a study published in the American Journal of Clinical Nutrition, about 90% of the variations researchers identified in the baseline number of calories participants expended over a 24-hour period came down to differences in fat mass and muscle mass. Your age has a measurable impact too. Researchers found that participants between 50 and 65 years of age had baseline metabolic rates that were 4.6% lower than participants between the ages of 20 and 30.

Fascinatingly, they reported: “No sex difference in any energy expenditure measurement could be found.” However, women do tend to have slower metabolisms than men, but it’s not because they’re women, it’s because on average, women are smaller and have less muscle mass.

So, let’s look into muscle mass differences. Findings published in the Journal of Applied Physiology reveal that women have, on average, about 67% of the muscle mass men do.

Women lag further behind when it comes to the muscle groups of the upper body than those of the lower body. A research team from the departments of Physical Education and Medicine at McMaster University in Hamilton, Canada set out to determine how gender differences influence strength and muscle fiber characteristics. They found that female participants had approximately 52% of the upper body strength and 66% of the lower body strength of men.

These differences appear to have more to do with the likelihood that men will have larger muscles than with innate sex-based differences, though. A study published in Ergonomics sought to measure the extent to which differences in strength between men and women can be explained by muscle size. Researchers found that when they adjusted their findings to take into account overall muscle mass as well as the size of specific muscle groups, 97% of sex-related differences were in strength. The researchers state that their findings suggest muscle size “almost entirely” accounts for the differences we expect to see between a man’s physical strength and a woman’s. In other words, if a man and woman have comparable muscle mass, they should be equally strong.

It appears that the vast majority of the differences we attribute to sex actually have to do with body composition. A woman and man with similar previous experience in terms of physical activity and comparative amounts of muscle and fat will perform similarly on standard measures of strength.

However, there are some differences between the ways men’s bodies and women’s bodies tend to respond to strength-training regimens and individual workout plans.

How Hormones Affect Female Muscle Growth

Hormones tend to be the first factor people point to when talking about physiological differences between women and men. It’s only logical, given that men’s increased muscle mass results from higher testosterone levels. Hormone levels fluctuate from person to person and over time, but on average, women produce far less testosterone than men do—between 15 and 20 times less, according to data sourced from the U.S. National Library of Medicine.

However, the question of testosterone levels isn’t as clear cut as we tend to think. In fact, some men have lower testosterone levels than some women do. After a team of researchers from the U.K. analyzed the hormone levels of elite athletes, they found significant overlap between testosterone levels for male competitors and female competitors. It’s worth noting that the hormone profiles of elite athletes differ from those of average individuals. It’s also highly likely that women with naturally higher levels of testosterone are more likely to excel at the elite level in certain physical disciplines. The main takeaway is that the idea that men have higher testosterone levels and therefore build new muscle more easily doesn’t entirely hold up.

Furthermore, did you know that testosterone is not the only hormone involved in building muscle mass? Estrogen, which as you may know, women typically produce at higher levels than men do, has also been shown to have significant benefits for muscle growth.

Studies done with animal subjects and well-controlled studies with human subjects support the idea that estrogen can help to prevent the breakdown of muscle tissue that often accompanies the aging process. It appears that estrogen has an overall positive impact when it comes to maintaining and increasing your lean muscle mass.

And an article published in Exercise and Sport Sciences Reviews presented experimental findings suggesting that estrogen may have an anabolic effect on muscles, meaning it supports muscle gain. It appears to do this primarily by lowering protein turnover, which slows the rate of catabolism (muscle breakdown), and enhancing the sensitivity of muscle tissue to resistance training.

Estrogen also boosts your metabolism, making it easier to cut your body fat percentage. While that doesn’t directly contribute to muscle growth, it does mean the new muscles you build will be more visible.

Women and Men Build Different Types of Muscles

We all have two general types of skeletal muscle fibers: slow-twitch, or Type 1, and fast-twitch, or Type 2. Type 1 muscles help power you through feats of endurance, like marathons. And the more Type 2 muscles you have, the better you perform on tests of explosive strength, like Olympic weight training.

There’s a clear divide between the average percentages of Type 1 and Type 2 muscle fibers that women and men typically have. According to Greg Nuckols, an experienced fitness writer who holds a BS in Exercise and Sports Science and three all-time world records for powerlifting, women typically have more Type 1 muscle fibers than men do, about 27% to 35% more. Women also tend to have greater capillary density.

Both give women an advantage in many ways. Greater capillary density means an increased ability to circulate blood through your muscle tissue to bring in fresh oxygen and clear out waste products. And having a higher percentage of Type 1 muscle fibers gives you an improved capacity for glucose and fatty acid oxidation, which translates to a decreased risk of chronic conditions linked to metabolic health, like diabetes and heart disease.

However, Type 2 muscle fibers are thicker, quicker to contract, and engage when your body nears maximum exertion. If you’re looking to increase your muscle mass and build strength so you can lift heavier and heavier weights, you need to recruit your Type 2 muscles. There’s no evidence that Type 1 muscle fibers can be transformed into Type 2 muscle fibers (or vice versa), which means there may always be a gap between the level of explosive strength an experienced female weight lifter can generate and the amount a male lifter at the same level can generate.

Maximizing Muscle Growth as a Woman

While men may have some innate advantages when it comes to building muscle mass, studies show that both men and women gain muscle at the same rate when they commit to workout routines like resistance training, weight training, and high-intensity interval training (HIIT).

Researchers from the University of Maryland Exercise Science and Wellness Research Laboratories conducted a study in which participants committed to a 6-month, whole-body strength-training program that worked for all the major muscle groups in both the upper and lower bodies.

They used MRI images to assess thigh and quadriceps muscle volume as well as mid-thigh muscle cross-sectional area before and after the strength-training program. Their findings showed that the thigh and quadriceps muscle volume increased significantly for all age and gender groups as a result of the strength-training program. The researchers found no significant differences related to either participant age or gender.

In some cases, women can make more significant strength and muscle gains than men. A study published in the International Journal of Sports Medicine examined how men and women responded to weight-training and resistance-training approaches. The researchers found that after following the same short-term training program, female participants made more significant strength increases than male participants did.

For women interested in optimizing their body composition by decreasing their body fat percentages and increasing their muscle mass, there are certain strategies you can put in place to maximize your muscle-building potential.

Train Strategically

When it comes to building muscle, the first step is to institute a strength-training regimen. For those seeking to rapidly increase muscle growth who are comfortable and able to perform high-intensity workouts, the most effective strength-training approach will involve lifting increasingly heavy weights. That might mean using barbell, kettlebells, dumbbells, or other types of weights.

Incorporating weightlifting into your training sessions encourages muscle growth because of the strain it places on your muscles. This wear and tear breaks down the muscle tissues. Then, during the recovery process that takes place while you sleep and on rest days, your muscles rebuild themselves. Each time this process takes place, your muscles grow bigger and stronger.

Adding high-intensity interval training to your exercise routine can also increase your muscle gains. This method of training involves short burst of intense exertion—a great tactic for recruiting your Type 2 muscles.

Increase Your Protein Intake

As you know, your muscles are made up of proteins. In order for your muscles to successfully rebuild themselves after workouts, you need to provide them with an adequate supply of dietary protein.

There’s no one-size-fits-all answer to the question of how much protein your muscles need to properly build and repair themselves. Factors like age, weight, activity level, and training goals will all influence the amount of protein an individual needs to consume.

Federal guidelines set the minimum recommended amount of protein consumption for adults at 17% to 21% of your daily calories, and that’s without taking weight training into consideration.

As Jim White, RD, ACSM, explained, resistance training increases the process of protein turnover. By eating proteins laden with all the essential amino acids, you’re providing your body with the raw materials it needs to build muscle.

According to the American College of Sports Medicine, if you’re looking to build muscle mass, you should aim to consume between 0.5 and 0.8 grams of protein per pound of body weight. That means a 150-pound woman, for example, should set a protein intake target of 75-120 grams of protein each day. It’s also important to consider the percentage of your overall calorie intake that comes from protein.

White, as well as other experts, recommends prioritizing the post-workout window for protein consumption as this has the biggest impact on muscle growth. Findings published in the Journal of the International Society of Sports Nutrition indicate that protein consumption before workouts can also be a key factor. Eating protein both before and after workouts can boost your performance, speed your recovery time, and increase your lean muscle mass.

Amino Acids Can Boost Female Muscle Growth

While it’s entirely possible to meet your body’s protein needs through diet alone, it can be helpful to add in high-quality supplements, including protein powders. Especially if you have a busy schedule that makes it challenging to consume enough protein during meal or snack times, it can be highly beneficial to provide your body with amino acids from other sources.

Researchers have found that certain supplements can be particularly helpful when it comes to building and maintaining muscle mass. If you’re wondering about the best amino acids for muscle growth, here are three to consider.

How amino acids can maximize female muscle growth.

1. Creatine

Creatine, an amino acid compound found naturally in the human body as well as in foods like red meat, has been the subject of hundreds of studies. If you’re lifting weights and looking to amplify your results, you may want to consider supplementing with creatine.

Media reports may have lead you to believe that creatine supplementation can adversely impact the health of your kidneys, but scientists have repeatedly and conclusively found that not to be the case.

After going over all available data on the short-, medium-, and long-term effects of creatine supplementation, researchers from the Higher Institute of Physical Education and Readaptation in Brussels, Belgium found no evidence that creatine causes liver dysfunction in healthy individuals (individuals with pre-existing kidney disease should avoid creatine). The researchers concluded that individuals who take creatine “do not report any adverse effects, but body mass increases.” They also noted that creatine may benefit the health of your heart and help reduce your risk of neurological diseases.

Studies show that supplementing with creatine can increase your lean body mass, enhance your anaerobic working capacity, and minimize the muscle damage caused by extreme exertion.

2. Beta-Alanine

This naturally occurring amino acid has also been the subject of extensive research.

One reason for this is that beta-alanine is the rate-limiting precursor of carnosine, an amino acid found in high concentrations in human skeletal muscle. One study on the effects of beta-alanine supplementation found that it can increase concentrations of carnosine in your muscles, which in turn helps to prevent muscular fatigue.

A separate study published in the Journal of the International Society of Sports Nutrition found pairing beta-alanine supplementation with high-intensity interval training (HIIT) can substantially increase both endurance and aerobic metabolism. It also showed a clear and impressive impact on subjects’ lean muscle mass.

Plus, a third study that examined how beta-alanine impacted anaerobic power output by using tests of physical strength such as timed sprints and a 90° bent-arm hang found that supplementing with beta-alanine improved participants’ results across all categories. Participants who supplemented with beta-alanine were able to achieve simultaneous weight loss and lean body mass increases.

3. Citrulline

Supplementing with citrulline can significantly increase your blood levels of not only this important amino acid, but two other crucial amino acids as well: ornithine and arginine. This can have a wide range of health benefits.

According to findings published in the The Journal of Strength & Conditioning Research, even a single dose of citrulline can improve your physical performance as measured by a flat barbell bench press. It can also reduce post-exercise muscle soreness. Participants were able to complete approximately 53% more repetitions and reported 40% less muscle soreness at both 24 and 48 hours afterward.

A separate study published in the British Journal of Sports Medicine showed that citrulline reduced muscular fatigue and improved muscle metabolism as measured by oxidative ATP production and the rate of phosphocreatine recovery after exercise.

All in all, it appears that this amino acid can improve endurance and speed up recovery time.

Greater Than the Sum of the Parts

Your muscles aren’t composed of single amino acids, but rather 20 separate amino acids. Building muscle mass requires a steady supply of all those amino acids. Nine of those are essential amino acids, meaning you must get them from the foods you eat or supplements you take.

While certain amino acids have been shown to have more dramatic results when it comes to muscle growth, your rate of muscle protein synthesis will be limited by whichever essential amino acid is in the shortest supply. That’s why some of the foremost experts on amino acids believe that taking an essential amino acid (EAA) blend is ultimately the most effective way to build your muscle mass. Using a supplement formulated to include all the required amino acid building blocks stimulates the production of new muscle tissue more effectively than any single amino acid could.